Mesotherapy began with Dr. M Pistor in France in 1952, with “meso” coming from mesoderm, the targeted superficial skin level. These were given in the skin for a with a variety of substances (the earliest being numbing medications such as procaine) and for variety of reasons but with no good controlled research trials. In 1981 Dr. Jacque Le Coz began using these techniques for athletic medicine using the skin as a controlled release delivery vehicle for local therapy of tendonitis and fasciitis.
The pioneers of Lipotherapy (mesotherapy technique used to treat fat accumulations) are Dr. Patricia Rittes and Dr. Roman Chubaty, under whom Dr. Berger trained. Phosphatidylcholine (lecithin of prescription grade purity) has been used intravenously since the 1950’s in cardiac related illnesses to reduce cholesterol and plaque. Dr. Rittes has done over 26,000 treatments of body fat and Dr. Chubaty has done over 1000 treatments using phosphatidylcholine. There is now good research showing this to be a safe, effective and simple technique
These injections are given in the skin in the treatment areas. The usual charge is $200 per symmetrical area each treatment, and the best improvements are seen with 4 treatments 2 weeks apart.
Areas treated are:
- male breasts
- love handles
- bra bulge (thorax)
- upper abdomen/midriff
- lower abdomen
- double chin/neck sling
- lipomas (benign fatty tumors)
Before & After

Research
What does the literature say? Are there any published data?
J Drugs Dermatol 2003 Oct;2(5):511-8 (ISSN: 1545-9616)
Hexsel D; Serra M; Mazzuco R; Dal’Forno T; Zechmeister D
Doris Hexsel Dermatologic Clinic, Porto Alegre, Brazil. dohexsel@zaz.com.br.
Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases. Recently, it has also been used in the treatment of localized fat deposits. We report on the authors’ clinical experience of the use of 250 mg/ml phosphatidylcholine injections in the treatment of subcutaneous fat deposits, showing the clinical response and side-effects. Volunteers received phosphatidylcholine injections in several areas of localized fat deposits, with a minimum interval of one week and mean interval of 15 days between applications. Laboratory tests were performed during the period of the drug use. Clinical results reflect that phosphatidylcholine was efficacious in reducing the fatty pads in the treated areas, with few side effects. From the authors’ point of view, the off-label use of phosphatidylcholine in the treatment of fatty pads and small areas of localized fat is safe, low cost, and effective.
